Mast Cell Activation Syndrome (MCAS) Diagnosis and Treatment Options
For short, mast Cell Activation Syndrome, or MCAS, is an illness that can turn from an inconvenience to life-threatening within seconds. It’s not uncommon for those with Mast Cell Activation Syndrome to be misdiagnosed for years, and as a result, it goes unmanaged for far too long.
Here are some of the symptoms of Mast Cell Activation Syndrome, along with treatment options to support obtain you started on the right path to managing your symptoms! ##. So you’re probably thinking, how does one go about actually treating Mast Cell Activation Syndrome? The rather forte to accomplish is to make sure you have the diagnosis. Here are a few ways to start figuring out if you might be suffering from this condition: —
Check for trigger foods and avoid them when possible.
Eat foods that are low on the allergen scale.
Don’t eat too many processed foods.
What is Mast Cell Activation Syndrome?
Mast cell activation syndrome is a disease of the immune system. The syndrome results from an excessive release of chemicals called mast cells. Mast cells are the region of the immune system. They contain chemicals that can cause swelling and other symptoms in tissues. Mast cell activation syndrome is an abnormality of this process.
It occurs when mast cells release chemicals that cause symptoms. The signs of mast cell activation syndrome are similar to allergies, chronic fatigue syndrome, fibromyalgia, irritable bowel syndrome, and other conditions.
Mast cell activation syndrome is an abnormality of this process. It occurs when mast cells release chemicals that cause symptoms. Mast cell activation syndrome symptoms are similar to allergies, chronic fatigue syndrome, fibromyalgia, irritable bowel syndrome, and other conditions—systemic Mastocytosis.
Symptoms vary from mild to severe. Mast cells are found throughout the body. They are especially abundant near the skin’s surface, in the nose, on the intestine lining, and in the lungs. Mast enclosure activation syndrome (MCAS) is an autoimmune condition with rashes, abdominal pain, chest pain, headache, diarrhea, and fatigue. The symptoms usually occur hours after consuming foods that trigger an immune response. The ensuing is a list of everyday meal triggers for people with MCAS.
Please note: This article is intended to provide general information and is not a substitute for medical advice. References:
Symptoms of Mast Cell Activation Syndrome
Mast Cell Activation Syndrome (MCAS) is a spectrum of diseases caused by an underlying genetic predisposition and environmental triggers.
Manifestation varies from person to person but can include any of the following: anxiety, atopic dermatitis, abdominal pain, asthma, eczema, nausea, diarrhea, cough, difficulty swallowing, rash, hives, itching, flushing, headaches, feeling feverish, wheezing, itchy eyes, sinus congestion, nasal congestion, trouble breathing, postnasal drip, congestion, phlegm, frequent urination, constipation, urinary tract infection, sleep problems, pain, and fatigue.
• Mental/emotional issues can include depression, panic attacks, anxiety, brain fog, mood swings, irritability, difficulty concentrating, being detached from reality, loss of memory, feeling suicidal, and increased risk of substance abuse.
What Is Incest?
There are different types of incest: biological parents and children, grandparents and grandchildren, aunts and nephews, uncles and nieces, step-parents and step-children, foster parents and foster children, and other relatives. Incest is illegal in all 50 states and is classified as a felony in most states. Incest is a crime because it is considered harmful to the public good. Studies show that incestuous relationships cause emotional harm and sometimes physical harm.
If you are the victim of an incest crime, no matter where you live, get help.
What causes Mast Cell Activation Syndrome?
Mast Cell Activation Syndrome, also known as Mastocytosis, is a rare disorder that causes the overproduction of mast cells. Mast cells are white blood cells that produce chemicals to protect the body from harmful substances, such as allergens and parasites. They again recreate a role in hives, healing, and tissue repair. Mast cells are mostly inactive, but they’re ready to release chemicals at the first sign of trouble.
Mast cell disorders include:
- Mastocytosis (mast cells accumulating in specific organs).
- Urticaria pigmentosa (also called mastocytoma or familial chronic urticaria).
- Mast cell activation syndrome (MCAS).
- Some cases of anaphylaxis.
In each case, skin rashes are a prominent feature.
The cause of Mastocytosis is unknown, and there is no cure. Mastocytoma (a subtype of urticaria pigmentosa) is inherited as an autosomal dominant disorder with incomplete penetrance.
Treatment for mastocytoma is mainly symptomatic. MCAS is characterized by numerous symptoms, including allergic reactions, gastrointestinal symptoms, and neurological symptoms. It is characterized by persistent GI symptoms, particularly abdominal pain, cramping, and bloating.
However, other more severe symptoms may be present, including mouth ulcers, fatigue, dizziness, fainting, tingling sensations in the hands and feet, swelling, shortness of breath, and weight loss.
One particular type of MCAS is mast cell activation syndrome (MCAS) with CNS involvement (MCCNS). The following is a case history of a young adult male diagnosed with MCCNS after a bad reaction to an antibiotic for an ear infection.
Over the next two years, he was hospitalized over 50 times and underwent numerous procedures to treat his symptoms, including removing one adrenal gland, placing IV lines, daily blood draws, frequent antihistamines, and lots of pain medications.
How is Mast Cell Activation Syndrome Treated?
Mast Cell Activation Syndrome is not typically treated with specific therapy, but rather the focus of treatment is to manage the symptoms of the syndrome. Mast Cell Activation Syndrome is not typically treated with specific therapy, but rather the focus of treatment is to manage the symptoms of the syndrome.
There are two treatment types, both of which are focused on managing the symptoms of Mast Cell Activation Syndrome. The first is an immunotherapy approach, which exposes the body to increasing doses of the substance that causes symptoms. The idea after this process is that it enables your body to build up tolerance gradually.
The second treatment is hydroxychloroquine, a drug typically used to treat rheumatoid arthritis and other autoimmune diseases. It is thought to work by inhibiting new vessel growth. The third is a combination of both treatments.
Researchers will assess the participants’ vascular health before and after treatment with either one or two of the three options. These assessments include examining their carotid arteries to see if any plaque has formed there and assessing their blood vessels for fatty deposits linked to cardiovascular disease.